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Clinical trials for Nitric Oxide

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
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    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   43873   clinical trials with a EudraCT protocol, of which   7292   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    223 result(s) found for: Nitric Oxide. Displaying page 1 of 12.
    1  2  3  4  5  6  7  8  9  Next» Last»»
    EudraCT Number: 2010-023529-39 Sponsor Protocol Number: RHM CHI 0548 Start Date*: 2011-02-18
    Sponsor Name:Southampton University Hopsitals NHS Trust
    Full Title: Reducing antibiotic tolerance using low dose nitric oxide in cystic fibrosis – a phase 2 pilot study
    Medical condition: Cystic Fibrosis
    Disease:
    Population Age: Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2005-000326-24 Sponsor Protocol Number: INOT41 Start Date*: 2005-10-27
    Sponsor Name:INO Therapeutics
    Full Title: The Effects of Nitric Oxide for Inhalation during Left Ventricular Assist Device (LVAD) Implantation.
    Medical condition: Acute right ventricular failure.
    Disease: Version SOC Term Classification Code Term Level
    7.0 10054933 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-000625-30 Sponsor Protocol Number: INOT22 Start Date*: 2004-07-21
    Sponsor Name:INO Therapeutics
    Full Title: Comparison of Supplemental Oxygen and Nitric Oxide for Inhalation Plus Oxygen in the Evaluation of the Reactivity of the Pulmonary Vasculature During Acute Pulmonary Vasodilator Testing
    Medical condition: : Nitric Oxide for inhalation at 800ppm, plus 100% O2, to be used to assess pulmonary vaso reactivity during Pulmonary Vasodilator Testing
    Disease:
    Population Age: Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: ES (Completed) GB (Completed)
    Trial results: View results
    EudraCT Number: 2005-005678-61 Sponsor Protocol Number: ESNOD-01 Start Date*: 2006-02-22
    Sponsor Name:University Hospital Tuebingen
    Full Title: Entwicklung einer Untersuchungsmethode zur Bestimmung des NO-Transferfaktors der Lunge Evaluierung der Methode und Normwerterhebung an gesunden Probanden (Development of a new method for steady-sta...
    Medical condition: Lung function testing (NO- and CO Transferfactor) in healthy subjects
    Disease:
    Population Age: Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2004-004928-12 Sponsor Protocol Number: VICER1 Start Date*: 2005-03-03
    Sponsor Name:INO Therapeutics AB
    Full Title: A pilot, unicenter, prospective, aleatorized, with parallel groups, controlled and open to evaluate the efficacy of the Nitric Oxide for Inhalation in the prevention of reperfusion in pulmonary donor
    Medical condition: pulmonary graft dysfunction
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: View results
    EudraCT Number: 2020-001329-30 Sponsor Protocol Number: 2020P000787 Start Date*: 2020-04-09
    Sponsor Name:Massachussetts General Hospital
    Full Title: Inhaled Nitric Oxide Gas Therapy in Mechanically Ventilated Patients with Severe Acute Respiratory Syndrome in COVID-19
    Medical condition: ARDS caused by COVID-19 infection
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2016-000338-23 Sponsor Protocol Number: 16013 Start Date*: 2016-03-21
    Sponsor Name:University of Nottingham
    Full Title: Does a low exhaled Nitric Oxide level exclude a clinical benefit from inhaled corticosteroids in suspected asthma; a double-blind, randomised, placebo controlled trial.
    Medical condition: suspected asthma people with asthma like symptoms
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2005-001525-28 Sponsor Protocol Number: ICL-INONAC1 Start Date*: 2006-03-24
    Sponsor Name:Imperial College London
    Full Title: INFLUENCE OF THE ANTIOXIDANT N-ACETYLCYSTEINE ON INHALED NITRIC OXIDE INDUCED PULMONARY RESPONSES FOLLOWING HUMAN LUNG ISCHAEMIA-REPERFUSION INJURY
    Medical condition: heart-lung transplantation
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2007-000936-21 Sponsor Protocol Number: 2007LF004B Start Date*: 2007-09-10
    Sponsor Name:Royal Brompton
    Full Title: THE EFFECT ON ALVEOLAR NITRIC OXIDE OF SALMETEROL, FLUTICASONE, AND IN COMBINATION, IN STABLE BRONCHIECTASIS.
    Medical condition: bronchiectasis.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10006445 Bronchiectasis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2020-001490-68 Sponsor Protocol Number: NCT04306393 Start Date*: 2020-04-15
    Sponsor Name:Stockholm County Council; Danderyd Hospital
    Full Title: Inhaled Nitric Oxide Gas Therapy in Mechanically Ventilated Patients with Severe Acute Respiratory Syndrome in COVID-19
    Medical condition: COVID-19 infection caused by SARS-CoV-2
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004862 10038700 Respiratory infection LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: View results
    EudraCT Number: 2008-006776-29 Sponsor Protocol Number: 081016 Start Date*: 2009-02-18
    Sponsor Name:Karolinska Institutet
    Full Title: NO som behandling vid knäproteskirurgi. Studie med avseende på anti-inflammatorisk modulation hos patienter som genomgår operation med ryggbedövning.
    Medical condition: Patienter som skall genomgå knäprotesoperation och skall ha bedövning i form av ryggbedövning (spinalanestes/epiduralanestesi).
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-001287-36 Sponsor Protocol Number: CTP-5 Start Date*: 2008-06-16
    Sponsor Name:Nitric BioTherapeutics, Inc
    Full Title: A Phase II Trial on the Reduction of Meticillin Resistant Staphylococcus Aureus in MRSA Positive Ulcers
    Medical condition: Ulcers in which the presence of meticillin resistant Staphylococcus aureus (MRSA) has been identified.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10045285 Ulcer LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2020-004994-27 Sponsor Protocol Number: 2020SW03 Start Date*: 2020-12-16
    Sponsor Name:Ashford and St Peter's Hospitals NHS Foundation Trust
    Full Title: Clinical Efficacy of Nitric Oxide Nasal Spray (NONS) for the Treatment of Mild COVID-19 Infection
    Medical condition: COVID-19
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2014-001029-34 Sponsor Protocol Number: 2014-BUDFOR-EL-47 Start Date*: 2015-10-07
    Sponsor Name:ELPEN Pharmaceutical Co. Inc
    Full Title: Evaluation of the effect of the inhaled combination budesonide -formoterol (Pulmoton® Elpenhaler®) in exhaled nitric oxide (FeNO) of patients with bronchial asthma.
    Medical condition: Bronchial Asthma
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-002312-29 Sponsor Protocol Number: INOT -27 Start Date*: 2005-01-10
    Sponsor Name:INO Therapeutics
    Full Title: The Effects of Nitric Oxide for Inhalation on the development of chronic lung disease in pre-term infants.
    Medical condition: Prevention of chronic lung disease in pre-term infants ( gestational age < 29 weeks) with respiratory distress.
    Disease: Version SOC Term Classification Code Term Level
    7.0 10054933 LLT
    Population Age: Preterm newborn infants, Under 18 Gender: Male, Female
    Trial protocol: FI (Completed) SE (Completed) GB (Completed) DE (Completed) BE (Completed) ES (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2004-004614-16 Sponsor Protocol Number: DIA-ALE-2004-01 Start Date*: 2005-09-29
    Sponsor Name:DIATER LABORATORIES S.A.
    Full Title: Alternaria alternata inmunotherapy effects on AMP and methacholine bronchial answer and on inflammation markers in exhaled air (nitric oxide) and in condensated air (pH and hydrogen peroxide) in a...
    Medical condition: Asthma and allergic rhinitis
    Disease:
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2022-003884-37 Sponsor Protocol Number: RONIN-CCV Start Date*: 2023-05-26
    Sponsor Name:Fernando Suarez Sipmann
    Full Title: Role of inhaled nitric oxide on right ventricular function and pulmonary vascular mechanics following cardiac surgery
    Medical condition: Patients in the immediate cardiac surgery post-operative period
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2017-004684-12 Sponsor Protocol Number: iNO_Protocol_V1.1_16.07.17 Start Date*: 2019-05-16
    Sponsor Name:Lady Cilento Children's Hospital
    Full Title: Nitric Oxide during Cardio Pulmonary Bypass during surgery for congenital heart defects: A Randomised Controlled Trial.
    Medical condition: Congenital heart disease ranks still within the top causes of infant mortality in industrialized countries. Despite considerable advances over the past decade, the exposure to cardiopulmonary bypas...
    Disease:
    Population Age: Newborns, Infants and toddlers, Under 18 Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2014-003338-15 Sponsor Protocol Number: RBHP2014ELJEZI Start Date*: 2014-12-01
    Sponsor Name:CHU de Clermont-Ferrand
    Full Title: Role of Nitric Oxide (NO) in pre-oxygenation before anesthetic induction in patients with Pulmonary Hypertension (PH) in cardiac surgery. Feasibility study.
    Medical condition: - Cardiac surgery open heart - Pulmonary Hypertension with PAPs> 40 mmHg secondary to left heart disease or COPD (class 2 or 3), diagnosed by preoperative right heart catheterization or transthora...
    Disease: Version SOC Term Classification Code Term Level
    18.0 100000004863 10017501 Functional disturbances following cardiac surgery LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-002931-95 Sponsor Protocol Number: LCC2010.01 Start Date*: 2008-01-30
    Sponsor Name:UZ Leuven
    Full Title: The Effects of Nitric Oxide for Inhalation on Myocardial Infarction Size.
    Medical condition: Myocardial Infarction
    Disease: Version SOC Term Classification Code Term Level
    14.1 10007541 - Cardiac disorders 10028596 Myocardial infarction PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed) DE (Prematurely Ended) HU (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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